First test of a “high-density injection” protocol for myogenic cell transplantation throughout large volumes of muscles in a Duchenne muscular dystrophy patient …

D Skuk, M Goulet, B Roy, V Piette, CH Côté… - Neuromuscular …, 2007 - Elsevier
A 26-years old Duchenne muscular dystrophy (DMD) patient received normal muscle-
precursor cells, proliferated in vitro and implanted in a thenar eminence, biceps brachii, and
in a portion of a gastrocnemius by injections placed 1mm from each other or less. Saline
was injected in the contralateral gastrocnemius. The patient was immunosuppressed with
tacrolimus. The protocol of cell transplantation was well tolerated and did not cause
permanent sequels. Some injected sites were biopsied at 1, 14 and 18 months post …