Protective role of Interleukin 27 (IL-27) gene polymorphisms in patients with ulcerative colitis
JK Yamamoto-Furusho, R Posadas-Sánchez… - Immunology …, 2016 - Elsevier
Ulcerative colitis (UC) is a chronic condition of unknown etiology and a polygenic disease.
The interleukin 27 (IL-27) have been implicated in the pathogenesis of several autoimmune
diseases including inflammatory bowel disease. Several polymorphisms of IL-27 have been
associated with several types of cancer and immune disorders. The aim of the present study
was to evaluate the association between IL-27 gene polymorphisms and the development of
UC. Four polymorphisms of IL-27p28 gene (rs181206, rs26528, rs17855750, and rs40837) …
The interleukin 27 (IL-27) have been implicated in the pathogenesis of several autoimmune
diseases including inflammatory bowel disease. Several polymorphisms of IL-27 have been
associated with several types of cancer and immune disorders. The aim of the present study
was to evaluate the association between IL-27 gene polymorphisms and the development of
UC. Four polymorphisms of IL-27p28 gene (rs181206, rs26528, rs17855750, and rs40837) …