Donor-specific antibodies are associated with antibody-mediated rejection, acute cellular rejection, bronchiolitis obliterans syndrome, and cystic fibrosis after lung …
LJ Lobo, RM Aris, J Schmitz, IP Neuringer - The Journal of Heart and Lung …, 2013 - Elsevier
BACKGROUND: Lung transplantation is limited by chronic lung allograft dysfunction. Acute
cellular rejection (ACR) is a risk factor for allograft dysfunction; however, the role of antibody-
mediated rejection (AMR) is not well characterized. METHODS: This was a retrospective
review from 2007 to 2011 of lung transplant recipients with human leukocyte antigen (HLA)
antibody testing using Luminex (Luminex Corp, Austin, TX) single-antigen beads. Statistics
included Fisher's exact test for significance. RESULTS: Donor-specific antibodies (DSA) …
cellular rejection (ACR) is a risk factor for allograft dysfunction; however, the role of antibody-
mediated rejection (AMR) is not well characterized. METHODS: This was a retrospective
review from 2007 to 2011 of lung transplant recipients with human leukocyte antigen (HLA)
antibody testing using Luminex (Luminex Corp, Austin, TX) single-antigen beads. Statistics
included Fisher's exact test for significance. RESULTS: Donor-specific antibodies (DSA) …