Sambamba: fast processing of NGS alignment formats
Bioinformatics, 2015•academic.oup.com
Sambamba is a high-performance robust tool and library for working with SAM, BAM and
CRAM sequence alignment files; the most common file formats for aligned next generation
sequencing data. Sambamba is a faster alternative to samtools that exploits multi-core
processing and dramatically reduces processing time. Sambamba is being adopted at
sequencing centers, not only because of its speed, but also because of additional
functionality, including coverage analysis and powerful filtering capability. Availability and …
CRAM sequence alignment files; the most common file formats for aligned next generation
sequencing data. Sambamba is a faster alternative to samtools that exploits multi-core
processing and dramatically reduces processing time. Sambamba is being adopted at
sequencing centers, not only because of its speed, but also because of additional
functionality, including coverage analysis and powerful filtering capability. Availability and …
Abstract
Summary: Sambamba is a high-performance robust tool and library for working with SAM, BAM and CRAM sequence alignment files; the most common file formats for aligned next generation sequencing data. Sambamba is a faster alternative to samtools that exploits multi-core processing and dramatically reduces processing time. Sambamba is being adopted at sequencing centers, not only because of its speed, but also because of additional functionality, including coverage analysis and powerful filtering capability.
Availability and implementation: Sambamba is free and open source software, available under a GPLv2 license. Sambamba can be downloaded and installed from http://www.open-bio.org/wiki/Sambamba.
Sambamba v0.5.0 was released with doi:10.5281/zenodo.13200.
Contact: j.c.p.prins@umcutrecht.nl
Oxford University Press