Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19
T Herold, V Jurinovic, C Arnreich, BJ Lipworth… - Journal of Allergy and …, 2020 - Elsevier
Background Coronavirus disease 2019 (COVID-19) can manifest as a viral-induced
hyperinflammation with multiorgan involvement. Such patients often experience rapid
deterioration and need for mechanical ventilation. Currently, no prospectively validated
biomarker of impending respiratory failure is available. Objective We aimed to identify and
prospectively validate biomarkers that allow the identification of patients in need of
impending mechanical ventilation. Methods Patients with COVID-19 who were hospitalized …
hyperinflammation with multiorgan involvement. Such patients often experience rapid
deterioration and need for mechanical ventilation. Currently, no prospectively validated
biomarker of impending respiratory failure is available. Objective We aimed to identify and
prospectively validate biomarkers that allow the identification of patients in need of
impending mechanical ventilation. Methods Patients with COVID-19 who were hospitalized …