[HTML][HTML] Diagnostic sensitivity of SILVAMP TB-LAM (FujiLAM) point-of-care urine assay for extra-pulmonary tuberculosis in people living with HIV

AD Kerkhoff, B Sossen, C Schutz… - European …, 2020 - Eur Respiratory Soc
AD Kerkhoff, B Sossen, C Schutz, EI Reipold, A Trollip, E Moreau, SG Schumacher, R Burton…
European Respiratory Journal, 2020Eur Respiratory Soc
Diagnosing tuberculosis (TB) in people living with HIV (PLHIV) remains challenging in part,
because of its diversity of clinical manifestations, including high rates of extra-pulmonary
and disseminated disease [1]. In particular, disseminated TB, involving multiple organ
systems, is associated with high mortality but often presents non-specifically, which may
hinder prompt diagnosis [2, 3]. Xpert MTB/RIF (Xpert; Cepheid, Sunnyvale, CA, USA), is
currently recommended by the World Health Organization (WHO) as the first line assay for …
Diagnosing tuberculosis (TB) in people living with HIV (PLHIV) remains challenging in part, because of its diversity of clinical manifestations, including high rates of extra-pulmonary and disseminated disease [1]. In particular, disseminated TB, involving multiple organ systems, is associated with high mortality but often presents non-specifically, which may hinder prompt diagnosis [2, 3]. Xpert MTB/RIF (Xpert; Cepheid, Sunnyvale, CA, USA), is currently recommended by the World Health Organization (WHO) as the first line assay for evaluating a subset of extra-pulmonary TB disease (EPTB) manifestations [4].
European Respiratory Society