Myositis ossificans following forcible manipulation of the leg. A rabbit model for the study of heterotopic bone formation.

JE Michelsson, G Granroth, LC Andersson - JBJS, 1980 - journals.lww.com
JE Michelsson, G Granroth, LC Andersson
JBJS, 1980journals.lww.com
The right hind limbs of forty-four rabbits were immobilized with the knee in extension for as
long as five weeks, except for a daily session of forcible mobilization lasting five minutes.
Within five weeks there was progressive heterotopic-bone formation in the quadriceps
muscle. The roentgenographic and histological changes were similar to those seen in
human myositis ossificans.
Abstract
The right hind limbs of forty-four rabbits were immobilized with the knee in extension for as long as five weeks, except for a daily session of forcible mobilization lasting five minutes. Within five weeks there was progressive heterotopic-bone formation in the quadriceps muscle. The roentgenographic and histological changes were similar to those seen in human myositis ossificans.
Lippincott Williams & Wilkins