Chromium effects on glucose tolerance and insulin sensitivity in persons at risk for diabetes mellitus

NDA Ali, Y Ma, J Reynolds, JP Wise Sr, SE Inzucchi… - Endocrine Practice, 2011 - Elsevier
Objective To investigate the effects of daily chromium picolinate supplementation on serum
measures of glucose tolerance and insulin sensitivity in patients at high risk for type 2
diabetes mellitus. Methods We conducted a randomized, double-blind, placebo-controlled,
modified cross-over clinical trial with 6-month sequences of intervention and placebo
followed by a 6-month postintervention assessment. Adult patients with impaired fasting
glucose, impaired glucose tolerance, or metabolic syndrome were enrolled. Participants …