Idiopathic CD4 lymphocytopenia: Pathogenesis, etiologies, clinical presentations and treatment strategies

H Yarmohammadi, C Cunningham-Rundles - Annals of Allergy, Asthma & …, 2017 - Elsevier
Abstract Background Idiopathic CD4 lymphocytopenia (ICL) is a rare condition characterized
by an unexplained deficit of circulating CD4 T cells leading to increased risk of serious
opportunistic infections. The pathogenesis, etiology, clinical presentation, and best treatment
options remain unclear. Objective To describe the clinical presentation, treatment strategies,
and outcome of patients with ICL seen in a single referral center. Methods In a retrospective
study, from January 1993 to January 2014, the demographic characteristics, clinical …