Study objectives To examine the central inspiratory drive response to hypoxia in patients
with obstructive sleep apnea (OSA), according to their circadian BP profile, and in healthy
control subjects. Another objective was to evaluate the relationships among sleep
architecture, hypoxic sensitivity, urinary catecholamine excretion, and BP in OSA patients.
Patients and interventions Polysomnography, 24-h ambulatory BP recording, and urinary
excretion of catecholamines were simultaneously examined in 24 consecutive OSA patients …