Massive chronic intervillositis of the placenta associated with malaria infection
J Ordi, MR Ismail, PJ Ventura, E Kahigwa… - The American journal …, 1998 - journals.lww.com
Massive chronic intervillositis (MCI) is an infrequently recognized placental lesion thought to
be of immunologic origin that has been associated with poor fetal outcome. It is
characterized by a prominent inflammatory infiltrate in the intervillous space, composed
mainly of monocytes and macrophages that can simulate a maternal malignant disorder
involving the placenta. The villi are characteristically spared. We report 74 cases of placental
malarial infection with morphologic features of MCI. In all cases, the massive inflammatory …
be of immunologic origin that has been associated with poor fetal outcome. It is
characterized by a prominent inflammatory infiltrate in the intervillous space, composed
mainly of monocytes and macrophages that can simulate a maternal malignant disorder
involving the placenta. The villi are characteristically spared. We report 74 cases of placental
malarial infection with morphologic features of MCI. In all cases, the massive inflammatory …