[HTML][HTML] Atp11p and Atp12p are assembly factors for the F1-ATPase in human mitochondria
ZG Wang, PS White, SH Ackerman - Journal of Biological Chemistry, 2001 - ASBMB
Atp11p and Atp12p were first described as proteins required for assembly of the F 1
component of the mitochondrial ATP synthase in Saccharomyces cerevisiae (Ackerman, SH,
and Tzagoloff, A.(1990) Proc. Natl. Acad. Sci. USA 87, 4986–4990). Here we report the
isolation of the cDNAs and the characterization of the human genes for Atp11p and Atp12p
and show that the human proteins function like their yeast counterparts. Human ATP11
spans 24 kilobase pairs in 9 exons and maps to 1p32. 3-p33, while ATP12 contains≥ 8 …
component of the mitochondrial ATP synthase in Saccharomyces cerevisiae (Ackerman, SH,
and Tzagoloff, A.(1990) Proc. Natl. Acad. Sci. USA 87, 4986–4990). Here we report the
isolation of the cDNAs and the characterization of the human genes for Atp11p and Atp12p
and show that the human proteins function like their yeast counterparts. Human ATP11
spans 24 kilobase pairs in 9 exons and maps to 1p32. 3-p33, while ATP12 contains≥ 8 …