Memory--a century of consolidation

JL McGaugh - Science, 2000 - science.org
Science, 2000science.org
The memory consolidation hypothesis proposed 100 years ago by Müller and Pilzecker
continues to guide memory research. The hypothesis that new memories consolidate slowly
over time has stimulated studies revealing the hormonal and neural influences regulating
memory consolidation, as well as molecular and cellular mechanisms. This review examines
the progress made over the century in understanding the time-dependent processes that
create our lasting memories.
The memory consolidation hypothesis proposed 100 years ago by Müller and Pilzecker continues to guide memory research. The hypothesis that new memories consolidate slowly over time has stimulated studies revealing the hormonal and neural influences regulating memory consolidation, as well as molecular and cellular mechanisms. This review examines the progress made over the century in understanding the time-dependent processes that create our lasting memories.
AAAS