[HTML][HTML] Internal ribosomal entry site (IRES) activity generates endogenous carboxyl-terminal domains of Cx43 and is responsive to hypoxic conditions
M Ul-Hussain, S Olk, B Schoenebeck… - Journal of Biological …, 2014 - ASBMB
Connexin43 (Cx43) is the most abundant gap junction protein in higher vertebrate
organisms and has been shown to be involved in junctional and non-junctional functions. In
addition to the expression of full-length Cx43, endogenously produced carboxyl-terminal
segments of Cx43 have been described and have been suggested to be involved in
manifold biological functions, such as hypoxic preconditioning and neuronal migration.
Molecular aspects, however, behind the separate generation of carboxyl-terminal segments …
organisms and has been shown to be involved in junctional and non-junctional functions. In
addition to the expression of full-length Cx43, endogenously produced carboxyl-terminal
segments of Cx43 have been described and have been suggested to be involved in
manifold biological functions, such as hypoxic preconditioning and neuronal migration.
Molecular aspects, however, behind the separate generation of carboxyl-terminal segments …