Backgroud Major depression is a frequent psychiatric complication among patients with
traumatic brain injury (TBI). To our knowledge, however, the clinical correlates of major
depression have not been extensively studied. Objective To determine the clinical,
neuropsychological, and structural neuroimaging correlates of major depression occurring
after TBI. Design Prospective, case-controlled, surveillance study conducted during the first
year after the traumatic episode occurred. Settings University hospital level I trauma center …