Abnormal ventral frontal response during performance of an affective go/no go task in patients with mania
BACKGROUND: Patients with mania show a behavioral bias toward positive information in
an emotional go/no go task. This is the converse of the bias toward negative information
seen in unipolar depression that we have recently related to the abnormal function of ventral
and medial prefrontal cortices (PFCs). The aim of this study was to investigate the neuronal
basis of the bias toward positive information in manic patients. METHODS: During
performance of an emotional go/no go task using functional magnetic resonance imaging, 8 …
an emotional go/no go task. This is the converse of the bias toward negative information
seen in unipolar depression that we have recently related to the abnormal function of ventral
and medial prefrontal cortices (PFCs). The aim of this study was to investigate the neuronal
basis of the bias toward positive information in manic patients. METHODS: During
performance of an emotional go/no go task using functional magnetic resonance imaging, 8 …