Muscular dystrophy represents a major unmet medical need; only palliative treatments exist
for this group of debilitating diseases. Because multiple forms of muscular dystrophy arise
from compromised sarcolemmal membrane integrity, a therapeutic approach that can target
this loss of membrane function could be applicable to a number of these distinct diseases.
One promising therapeutic approach involves the process the cell uses to repair injuries to
the plasma membrane. Recent discoveries of genes associated with the membrane repair …