[HTML][HTML] Thrombin generation in morbid obesity: significant reduction after weight loss
L Ay, HP Kopp, JM Brix, C Ay, P Quehenberger… - Journal of Thrombosis …, 2010 - Elsevier
Background: Patients with morbid obesity (MO; body mass index> 40 kg m− 2) suffer from an
increased risk of cardiovascular disease, stroke, venous thromboembolism and all‐cause
mortality. Objectives: Because weight loss by bariatric surgery reduces cardiovascular and
all‐cause mortality, we hypothesized that the plasmatic clotting system might be involved in
cardiovascular risk. Patients/Methods: Thirty‐six MO patients [mean age 42 (±13) years; 29
female) were investigated before and 2 years after bariatric surgery. Thrombin generation …
increased risk of cardiovascular disease, stroke, venous thromboembolism and all‐cause
mortality. Objectives: Because weight loss by bariatric surgery reduces cardiovascular and
all‐cause mortality, we hypothesized that the plasmatic clotting system might be involved in
cardiovascular risk. Patients/Methods: Thirty‐six MO patients [mean age 42 (±13) years; 29
female) were investigated before and 2 years after bariatric surgery. Thrombin generation …