Haemostasis consists of a complicated sequence of events designed to prevent excessive
blood loss in case of vessel wall injury. The haemostatic system is in a delicate balance
between pro-and antihaemostatic processes. Alterations in the system may lead to either a
bleeding diathesis or thrombotic disorder. Liver failure is accompanied by multiple changes
in the haemostatic system. As many proteins involved in haemostasis are synthesized by the
liver, reduced plasma levels are found when the synthesis function of the liver becomes …