[HTML][HTML] Downregulation of signal transduction and STAT3 expression exacerbates oxidative stress mediated by NLRP3 inflammasome
H Bai, QF Zhang, JJ Duan, DJ Yu… - Neural regeneration …, 2018 - journals.lww.com
Activated nucleotide binding to the oligonucleotide receptor protein 3 (NLRP3)
inflammasome is possibly involved in the pathogenesis of Alzheimer's disease through
oxidative stress and neurogenic inflammation. Low expression of the signal transducer and
activator of transcription 3 (STAT3) gene may promote the occurrence of neurodegenerative
diseases to some extent. To clarify the roles of the NLRP3 inflammasome and STAT3
expression in oxidative stress,(1) SHSY5Y cells were incubated with 1 mM H 2 O 2 to induce …
inflammasome is possibly involved in the pathogenesis of Alzheimer's disease through
oxidative stress and neurogenic inflammation. Low expression of the signal transducer and
activator of transcription 3 (STAT3) gene may promote the occurrence of neurodegenerative
diseases to some extent. To clarify the roles of the NLRP3 inflammasome and STAT3
expression in oxidative stress,(1) SHSY5Y cells were incubated with 1 mM H 2 O 2 to induce …