[HTML][HTML] LIGHT/HVEM/LTβR interaction as a target for the modulation of the allogeneic immune response in transplantation
ML del Rio, P Schneider, C Fernandez-Renedo… - American Journal of …, 2013 - Elsevier
The exchange of information during interactions of T cells with dendritic cells, B cells or other
T cells regulates the course of T, B and DC-cell activation and their differentiation into
effector cells. The tumor necrosis factor superfamily member LIGHT (homologous to
lymphotoxin, exhibits inducible expression and competes with HSV glycoprotein D for
binding to herpesvirus entry mediator, a receptor expressed on T lymphocytes) is transiently
expressed upon T cell activation and modulates CD8 T cell-mediated alloreactive responses …
T cells regulates the course of T, B and DC-cell activation and their differentiation into
effector cells. The tumor necrosis factor superfamily member LIGHT (homologous to
lymphotoxin, exhibits inducible expression and competes with HSV glycoprotein D for
binding to herpesvirus entry mediator, a receptor expressed on T lymphocytes) is transiently
expressed upon T cell activation and modulates CD8 T cell-mediated alloreactive responses …