Mechanisms of DNA Repair by Photolyase and Excision Nuclease (Nobel Lecture).

A Sancar - Angewandte Chemie (International ed. in English), 2016 - europepmc.org
A Sancar
Angewandte Chemie (International ed. in English), 2016europepmc.org
Ultraviolet light damages DNA by converting two adjacent thymines into a thymine dimer
which is potentially mutagenic, carcinogenic, or lethal to the organism. This damage is
repaired by photolyase and the nucleotide excision repair system in E. coli by nucleotide
excision repair in humans. The work leading to these results is presented by Aziz Sancar in
his Nobel Lecture.
Ultraviolet light damages DNA by converting two adjacent thymines into a thymine dimer which is potentially mutagenic, carcinogenic, or lethal to the organism. This damage is repaired by photolyase and the nucleotide excision repair system in E. coli by nucleotide excision repair in humans. The work leading to these results is presented by Aziz Sancar in his Nobel Lecture.
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