The who, where, and when of IgE in allergic airway disease
M Dullaers, R De Bruyne, F Ramadani… - Journal of Allergy and …, 2012 - Elsevier
Allergic asthma and allergic rhinitis/conjunctivitis are characterized by a TH2-dominated
immune response associated with increased serum IgE levels in response to inhaled
allergens. Because IgE is a key player in the induction and maintenance of allergic
inflammation, it represents a prime target for therapeutic intervention. However, our
understanding of IgE biology remains fragmentary. This article puts together our current
knowledge on IgE in allergic airway diseases with a special focus on the identity of IgE …
immune response associated with increased serum IgE levels in response to inhaled
allergens. Because IgE is a key player in the induction and maintenance of allergic
inflammation, it represents a prime target for therapeutic intervention. However, our
understanding of IgE biology remains fragmentary. This article puts together our current
knowledge on IgE in allergic airway diseases with a special focus on the identity of IgE …