[PDF][PDF] Expanding roles for SREBP in metabolism
W Shao, PJ Espenshade - Cell metabolism, 2012 - cell.com
Cell metabolism, 2012•cell.com
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular
lipogenesis and lipid homeostasis. Recent studies reveal expanding roles for SREBPs with
the description of new regulatory mechanisms, the identification of unexpected
transcriptional targets, and the discovery of functions for SREBPs in type II diabetes, cancer,
immunity, neuroprotection, and autophagy.
lipogenesis and lipid homeostasis. Recent studies reveal expanding roles for SREBPs with
the description of new regulatory mechanisms, the identification of unexpected
transcriptional targets, and the discovery of functions for SREBPs in type II diabetes, cancer,
immunity, neuroprotection, and autophagy.
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesis and lipid homeostasis. Recent studies reveal expanding roles for SREBPs with the description of new regulatory mechanisms, the identification of unexpected transcriptional targets, and the discovery of functions for SREBPs in type II diabetes, cancer, immunity, neuroprotection, and autophagy.
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