Pneumonia due to Cryptococcus neoformans in a patient receiving infliximab: possible zoonotic transmission from a pet cockatiel

RK Shrestha, JK Stoller, G Honari, GW Procop… - Respiratory …, 2004 - rc.rcjournal.com
RK Shrestha, JK Stoller, G Honari, GW Procop, SM Gordon
Respiratory care, 2004rc.rcjournal.com
The use of humanized antibody against tumor necrosis factor alpha (TNF-α) may increase
the risk of various opportunistic infections, including tuberculosis and fungal infections. We
report a case of cryptococcal pneumonia in a patient who was taking infliximab for
rheumatoid arthritis. A temporally related exposure history raised the possibility that our
patient acquired the infection from his pet cockatiel. It seems prudent to advise patients
receiving infliximab to avoid exposure to pet avian excreta.
The use of humanized antibody against tumor necrosis factor alpha (TNF-α) may increase the risk of various opportunistic infections, including tuberculosis and fungal infections. We report a case of cryptococcal pneumonia in a patient who was taking infliximab for rheumatoid arthritis. A temporally related exposure history raised the possibility that our patient acquired the infection from his pet cockatiel. It seems prudent to advise patients receiving infliximab to avoid exposure to pet avian excreta.
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