Achalasia is an esophageal motor disorder characterized by abnormal relaxation of the
lower esophageal sphincter and absence of progressive peristalsis in the esophageal body.
Previous studies evaluating esophagomyotomy and esophageal resection specimens have
shown the presence of myenteric inflammation to be a consistent and early pathologic
change in patients with achalasia. Thus, the goal of this study was to determine the
immunohistochemical characteristics of the inflammatory infiltrate within the myenteric …