[HTML][HTML] Bone formation: The nuclear matrix reloaded
DL Ellies, R Krumlauf - Cell, 2006 - cell.com
DL Ellies, R Krumlauf
Cell, 2006•cell.comIn this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear
matrix protein Satb2 represses Hoxa2 expression and acts with other regulatory proteins to
promote osteoblast differentiation. This work suggests a molecular mechanism that enables
the integration of patterning and differentiation during bone formation.
matrix protein Satb2 represses Hoxa2 expression and acts with other regulatory proteins to
promote osteoblast differentiation. This work suggests a molecular mechanism that enables
the integration of patterning and differentiation during bone formation.
In this issue of Cell, Grosschedl and colleagues (Dobreva et al., 2006) report that the nuclear matrix protein Satb2 represses Hoxa2 expression and acts with other regulatory proteins to promote osteoblast differentiation. This work suggests a molecular mechanism that enables the integration of patterning and differentiation during bone formation.
cell.com