[PDF][PDF] Nutrient competition: a new axis of tumor immunosuppression

M Sukumar, R Roychoudhuri, NP Restifo - Cell, 2015 - cell.com
Cell, 2015cell.com
It is thought that cancer cells engage in Warburg metabolism to meet intrinsic biosynthetic
requirements of cell growth and proliferation. Papers by Chang et al. and Ho et al. show that
Warburg metabolism enables tumor cells to restrict glucose availability to T cells,
suppressing anti-tumor immunity.
It is thought that cancer cells engage in Warburg metabolism to meet intrinsic biosynthetic requirements of cell growth and proliferation. Papers by Chang et al. and Ho et al. show that Warburg metabolism enables tumor cells to restrict glucose availability to T cells, suppressing anti-tumor immunity.
cell.com