Survival of invasive breast cancer according to the Nottingham Prognostic Index in cases diagnosed in 1990–1999
RW Blamey, IO Ellis, SE Pinder, AHS Lee… - European journal of …, 2007 - Elsevier
RW Blamey, IO Ellis, SE Pinder, AHS Lee, RD Macmillan, DAL Morgan, JFR Robertson…
European journal of cancer, 2007•ElsevierThe Nottingham Prognostic Index (NPI) is a well established and widely used method of
predicting survival of operable primary breast cancer. AIMS: Primary: To present the updated
survival figures for each NPI Group. Secondary: From the observations to suggest reasons
for the reported fall in mortality from breast cancer. METHODS: The NPI is compiled from
grade, size and lymph node status of the primary tumour. Consecutive cases diagnosed and
treated at Nottingham City Hospital in 1980–1986 (n= 892) and 1990–1999 (n= 2238) are …
predicting survival of operable primary breast cancer. AIMS: Primary: To present the updated
survival figures for each NPI Group. Secondary: From the observations to suggest reasons
for the reported fall in mortality from breast cancer. METHODS: The NPI is compiled from
grade, size and lymph node status of the primary tumour. Consecutive cases diagnosed and
treated at Nottingham City Hospital in 1980–1986 (n= 892) and 1990–1999 (n= 2238) are …
The Nottingham Prognostic Index (NPI) is a well established and widely used method of predicting survival of operable primary breast cancer.
AIMS
Primary: To present the updated survival figures for each NPI Group.
Secondary
From the observations to suggest reasons for the reported fall in mortality from breast cancer.
METHODS
The NPI is compiled from grade, size and lymph node status of the primary tumour. Consecutive cases diagnosed and treated at Nottingham City Hospital in 1980–1986 (n=892) and 1990–1999 (n=2238) are compared. Changes in protocols towards earlier diagnosis and better case management were made in the late 1980s between the two data sets.
RESULTS
Case survival (Breast Cancer Specific) at 10 years has improved overall from 55% to 77%. Within all Prognostic groups there are high relative and absolute risk reductions. The distribution of cases to Prognostic groups shows only a small increase in the numbers in better groups.
CONCLUSION
The updated survival figures overall and for each Prognostic group for the NPI are presented.
Elsevier