An increased concentration of end products of lipid peroxidation is the evidence most
frequently quoted for the involvement of free radicals in human disease. However, it is likely
that increased oxidative damage occurs in most, if not all, human diseases and plays a
significant pathological role in only some of them. For example, peroxidation appears to be
important in atherosclerosis and in worsening the initial tissue injury caused by ischemic or
traumatic brain damage. Oxidative stress can damage many biological molecules; indeed …