Feedback loops shape cellular signals in space and time
O Brandman, T Meyer - Science, 2008 - science.org
Science, 2008•science.org
Positive and negative feedback loops are common regulatory elements in biological
signaling systems. We discuss core feedback motifs that have distinct roles in shaping
signaling responses in space and time. We also discuss approaches to experimentally
investigate feedback loops in signaling systems.
signaling systems. We discuss core feedback motifs that have distinct roles in shaping
signaling responses in space and time. We also discuss approaches to experimentally
investigate feedback loops in signaling systems.
Positive and negative feedback loops are common regulatory elements in biological signaling systems. We discuss core feedback motifs that have distinct roles in shaping signaling responses in space and time. We also discuss approaches to experimentally investigate feedback loops in signaling systems.
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