[HTML][HTML] Elevated procoagulant microparticles expressing endothelial and platelet markers in essential thrombocythemia

MC Trappenburg, M van Schilfgaarde, M Marchetti… - …, 2009 - ncbi.nlm.nih.gov
MC Trappenburg, M van Schilfgaarde, M Marchetti, HM Spronk, H ten Cate, A Leyte…
haematologica, 2009ncbi.nlm.nih.gov
Background Most cell types, including blood-and vascular cells, produce microparticles
upon activation. Since cellular microparticles are known to be elevated in thromboembolic
diseases, we hypothesized a role for microparticles in the pathogenesis of thrombosis in
essential thrombocythemia.
Abstract
Background
Most cell types, including blood-and vascular cells, produce microparticles upon activation. Since cellular microparticles are known to be elevated in thromboembolic diseases, we hypothesized a role for microparticles in the pathogenesis of thrombosis in essential thrombocythemia.
ncbi.nlm.nih.gov