Establishment of an orthotopic tumour model for hepatocellular carcinoma and non-invasive in vivo tumour imaging by high resolution ultrasound in mice
V Schmitz, L Tirado-Ledo, K Tiemann, E Raskopf… - Journal of …, 2004 - Elsevier
BACKGROUND/AIMS: In this study we established an orthotopic tumour model for
hepatocellular carcinoma and evaluated a non-invasive high resolution ultrasound
technique for diagnosis and follow-up of intrahepatic HCC. METHODS: Orthotopic liver
tumours were induced by intrahepatic tumour cell injection of 105 Hepa129 hepatoma cells.
Tumour establishment and growth were assessed by explorative laparotomy, ultrasound
technique and hepatectomy one and two weeks after tumour cell implantation. Tumour …
hepatocellular carcinoma and evaluated a non-invasive high resolution ultrasound
technique for diagnosis and follow-up of intrahepatic HCC. METHODS: Orthotopic liver
tumours were induced by intrahepatic tumour cell injection of 105 Hepa129 hepatoma cells.
Tumour establishment and growth were assessed by explorative laparotomy, ultrasound
technique and hepatectomy one and two weeks after tumour cell implantation. Tumour …