Effect of temporary ischemia upon development and histological patterns of acute pancreatitis in the rat

H Spormann, A Sokolowski, G Letko - Pathology-Research and Practice, 1989 - Elsevier
To study the importance of a disturbed energy metabolism for the development of acute
pancreatitis (AP) rats pretreated either by induction of a juice edema or by intraductal trypsin
instillation were subjected to temporary pancreatic ischemia. By means of a scoring system
quality and quantity of pathomorphologic parameters were quantified 24 h postoperatively.
There was a clear correlation between macroscopic and histologic scores independent of
the model used. While a juice edema or 40 min ischemia alone did not induce AP, a …