[HTML][HTML] Transitional B lymphocytes are associated with protection from kidney allograft rejection: a prospective study
S Shabir, J Girdlestone, D Briggs, B Kaul… - American Journal of …, 2015 - Elsevier
Recent cross-sectional studies suggest an important role for transitional B lymphocytes
(CD19+ CD24hiCD38hi) in promoting transplant tolerance, and protecting from late antibody-
mediated rejection (ABMR). However, prospective studies are lacking. This study enrolled
73 de novo transplant recipients, and collected serial clinical, immunological and
biochemical information over 48±6 months. Cell phenotyping was conducted immediately
prior to transplantation, and then on five occasions during the first year posttransplantation …
(CD19+ CD24hiCD38hi) in promoting transplant tolerance, and protecting from late antibody-
mediated rejection (ABMR). However, prospective studies are lacking. This study enrolled
73 de novo transplant recipients, and collected serial clinical, immunological and
biochemical information over 48±6 months. Cell phenotyping was conducted immediately
prior to transplantation, and then on five occasions during the first year posttransplantation …