Adipose-derived stem cells enhance primary tendon repair: biomechanical and immunohistochemical evaluation

CA Uysal, M Tobita, H Hyakusoku, H Mizuno - Journal of Plastic …, 2012 - Elsevier
BACKGROUND: Primary tendon repair aims at increased tensile strength at the time of
mobilisation. Tendon repair and regeneration using mesenchymal stem cells have been
described in different studies; however, adipose-derived stem cell (ASC) use for tendon
regeneration and repair has recently been taken into consideration. In this study, we sought
to determine whether ASCs would be beneficial in primary tendon healing. MATERIALS
AND METHODS: Both the Achilles tendons of rabbits (n= 6) were incised and consequently …