Clostridium difficile–associated diarrhea: a review
E Mylonakis, ET Ryan… - Archives of Internal …, 2001 - jamanetwork.com
Clostridium difficilecauses 300 000 to 3 000 000 cases of diarrhea and colitis in the United
States every year. Antibiotics most frequently associated with the infection are clindamycin,
ampicillin, amoxicillin, and cephalosporins, but all antibiotics may predispose patients toC
difficileinfection. The clinical presentation varies from asymptomatic colonization to mild
diarrhea to severe debilitating disease, with high fever, severe abdominal pain, paralytic
ileus, colonic dilation (or megacolon), or even perforation. The most sensitive and specific …
States every year. Antibiotics most frequently associated with the infection are clindamycin,
ampicillin, amoxicillin, and cephalosporins, but all antibiotics may predispose patients toC
difficileinfection. The clinical presentation varies from asymptomatic colonization to mild
diarrhea to severe debilitating disease, with high fever, severe abdominal pain, paralytic
ileus, colonic dilation (or megacolon), or even perforation. The most sensitive and specific …