[HTML][HTML] Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice

NC Bal, S Singh, FCG Reis, SK Maurya, S Pani… - Journal of Biological …, 2017 - ASBMB
Thermogenesis is an important homeostatic mechanism essential for survival and normal
physiological functions in mammals. Both brown adipose tissue (BAT)(ie uncoupling protein
1 (UCP1)-based) and skeletal muscle (ie sarcolipin (SLN)-based) thermogenesis processes
play important roles in temperature homeostasis, but their relative contributions differ from
small to large mammals. In this study, we investigated the functional interplay between
skeletal muscle-and BAT-based thermogenesis under mild versus severe cold adaptation by …