[HTML][HTML] Active idiotypic vaccination versus control immunotherapy for follicular lymphoma
Journal of clinical oncology, 2014•ncbi.nlm.nih.gov
Purpose Idiotypes (Ids), the unique portions of tumor immunoglobulins, can serve as targets
for passive and active immunotherapies for lymphoma. We performed a multicenter,
randomized trial comparing a specific vaccine (MyVax), comprising Id chemically coupled to
keyhole limpet hemocyanin (KLH) plus granulocyte macrophage colony-stimulating factor
(GM-CSF) to a control immunotherapy with KLH plus GM-CSF.
for passive and active immunotherapies for lymphoma. We performed a multicenter,
randomized trial comparing a specific vaccine (MyVax), comprising Id chemically coupled to
keyhole limpet hemocyanin (KLH) plus granulocyte macrophage colony-stimulating factor
(GM-CSF) to a control immunotherapy with KLH plus GM-CSF.
Abstract
Purpose
Idiotypes (Ids), the unique portions of tumor immunoglobulins, can serve as targets for passive and active immunotherapies for lymphoma. We performed a multicenter, randomized trial comparing a specific vaccine (MyVax), comprising Id chemically coupled to keyhole limpet hemocyanin (KLH) plus granulocyte macrophage colony-stimulating factor (GM-CSF) to a control immunotherapy with KLH plus GM-CSF.
ncbi.nlm.nih.gov