Experimental whooping cough

CC Huang, PM Chen, JK Kuo, WH Chiu… - … England Journal of …, 1962 - Mass Medical Soc
CC Huang, PM Chen, JK Kuo, WH Chiu, ST Lin, HS Lin, YC Lin
New England Journal of Medicine, 1962Mass Medical Soc
MANY questions about the immunologic mechanism responsible for the permanence of
immunity after an attack of whooping cough are still obscure, in spite of a large number of
clinical and experimental studies. It was considered worthwhile, therefore, to reinvestigate
the problem in animals under more uniform conditions. The following is a report on such
studies in Taiwan monkeys in which paroxysmal cough developed after an inoculation of
Haemophilus pertussis. Materials and Methods The animals used in the experiments were …
MANY questions about the immunologic mechanism responsible for the permanence of immunity after an attack of whooping cough are still obscure, in spite of a large number of clinical and experimental studies. It was considered worthwhile, therefore, to reinvestigate the problem in animals under more uniform conditions. The following is a report on such studies in Taiwan monkeys in which paroxysmal cough developed after an inoculation of Haemophilus pertussis.
Materials and Methods
The animals used in the experiments were normal young Taiwan monkeys, Macaca cyclopsis, weighing from 550 to 1875 gm. All monkeys were kept under preliminary observation to . . .
The New England Journal Of Medicine