[PDF][PDF] The use of convalescent human serum in influenza pneumonia—a preliminary report

LW McGuire, WR Redden - American journal of public …, 1918 - ajph.aphapublications.org
LW McGuire, WR Redden
American journal of public health, 1918ajph.aphapublications.org
WE are all aware of the high degree of fatality resulting from the pneumonia following the in-
fluenza of the present epidemic. All of our deaths have been due to the pneumonia
complication and none to the in-fluenza as such. Here at the Naval Hos-pital, the percentage
in the first groups reached as high as 50 to 60, and more recently the mortality has dropped
to 30 per cent. No doubt this complication will continue to give a high mortality rate,
especially when the disease invades new territory. For this reason, the authors have …
WE are all aware of the high degree of fatality resulting from the pneumonia following the in-fluenza of the present epidemic. All of our deaths have been due to the pneumonia complication and none to the in-fluenza as such. Here at the Naval Hos-pital, the percentage in the first groups reached as high as 50 to 60, and more recently the mortality has dropped to 30 per cent. No doubt this complication will continue to give a high mortality rate, especially when the disease invades new territory. For this reason, the authors have decided to make public their results in thetreatment of a small group of cases, by the use of serum from pa-tients convalescing from pneumonia, fol-lowing an attack of influenza. It will be readily seen that a complete report at this time isout of the question, but we hope to present sufficient data to indicate the possibility in the use of convalescent serum so that further work can be carried on in territory wherethe disease is now ac-tive, and where proper equipment is at hand to carryout the necessary labora-tory details.
The observation and treatment, by the writers, of over four hundred cases of influenza pneumonia in this hospital has afforded opportunity to compare the various methods of treatment with a fair degree of accuracy. The use of serum from convalescent in-fluenza pneumonia patients was suggested by the junior writer as possibly having curative value, because of probable anti-
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