Murine cerebral malaria: the whole story

NH Hunt, GE Grau, C Engwerda, SR Barnum… - Trends in …, 2010 - cell.com
NH Hunt, GE Grau, C Engwerda, SR Barnum, H van der Heyde, DS Hansen, L Schofield…
Trends in parasitology, 2010cell.com
],'The value of the mouse model in identifying pathological processes or therapeutic
interventions in human cerebral malaria is questionable.'Surprisingly, this conclusion was
presented without discussion of any of the numerous similarities between the cerebral
syndromes caused by Plasmodium falciparum in humans and the P. berghei ANKA strain in
mice that have been described in several detailed reviews (for example, Refs [
],‘The value of the mouse model in identifying pathological processes or therapeutic interventions in human cerebral malaria is questionable.’Surprisingly, this conclusion was presented without discussion of any of the numerous similarities between the cerebral syndromes caused by Plasmodium falciparum in humans and the P. berghei ANKA strain in mice that have been described in several detailed reviews (for example, Refs [
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