Symptoms and signs of chronic fatigue syndrome

AL Komaroff, D Buchwald - Reviews of Infectious Diseases, 1991 - academic.oup.com
Reviews of Infectious Diseases, 1991academic.oup.com
This review summarizes the symptoms and signs seen in patients with chronic fatigue
syndrome (CFS). It is based on the authors' experience with two cohorts of∼ 510 patients
with chronic debilitating fatigue and on the reported experience of other investigators with
similar patients. The most characteristic symptoms of CFS are the sudden onset of an
infectious-type illness, the subsequent chronic and debilitating fatigue, and postexertional
malaise; many patients also have recurrent fevers, pharyngitis, adenopathy, myalgias, sleep …
Abstract
This review summarizes the symptoms and signs seen in patients with chronic fatigue syndrome (CFS). It is based on the authors' experience with two cohorts of ∼510 patients with chronic debilitating fatigue and on the reported experience of other investigators with similar patients. The most characteristic symptoms of CFS are the sudden onset of an infectious-type illness, the subsequent chronic and debilitating fatigue, and postexertional malaise; many patients also have recurrent fevers, pharyngitis, adenopathy, myalgias, sleep disorders, and cognitive impairment.
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