[HTML][HTML] Definition of cancer cachexia: effect of weight loss, reduced food intake, and systemic inflammation on functional status and prognosis
KC Fearon, AC Voss, DS Hustead - The American journal of clinical …, 2006 - Elsevier
Background: Cancer cachexia is a multifactorial syndrome that is poorly defined. Objective:
Our objective was to evaluate whether a 3-factor profile incorporating weight loss (≥ 10%),
low food intake (≤ 1500 kcal/d), and systemic inflammation (C-reactive protein≥ 10 mg/L)
might relate better to the adverse functional aspects of cachexia and to a patient's overall
prognosis than will weight loss alone. Design: One hundred seventy weight-losing (≥ 5%)
patients with advanced pancreatic cancer were screened for nutritional status, functional …
Our objective was to evaluate whether a 3-factor profile incorporating weight loss (≥ 10%),
low food intake (≤ 1500 kcal/d), and systemic inflammation (C-reactive protein≥ 10 mg/L)
might relate better to the adverse functional aspects of cachexia and to a patient's overall
prognosis than will weight loss alone. Design: One hundred seventy weight-losing (≥ 5%)
patients with advanced pancreatic cancer were screened for nutritional status, functional …