Annexin A1: shifting the balance towards resolution and repair

G Leoni, A Nusrat - Biological chemistry, 2016 - degruyter.com
G Leoni, A Nusrat
Biological chemistry, 2016degruyter.com
Epithelial barriers play an important role in regulating mucosal homeostasis. Upon injury,
the epithelium and immune cells orchestrate repair mechanisms that re-establish
homeostasis. This process is highly regulated by protein and lipid mediators such as
Annexin A1 (ANXA1). In this review, we focus on the pro-repair properties of ANXA1.
Abstract
Epithelial barriers play an important role in regulating mucosal homeostasis. Upon injury, the epithelium and immune cells orchestrate repair mechanisms that re-establish homeostasis. This process is highly regulated by protein and lipid mediators such as Annexin A1 (ANXA1). In this review, we focus on the pro-repair properties of ANXA1.
De Gruyter