Moderate exercise training decreases inflammation in transgenic sickle cell mice
Chronic systemic inflammation is a pathophysiological feature of sickle cell disease (SCD).
Considering that regular exercise exerts multiple beneficial health effects including anti-
inflammatory actions, we investigated whether a treadmill training program could minimize
the inflammatory state in transgenic sickle cell (SS) mice. To test this hypothesis, SS mice
were subjected to a treadmill training protocol of 1 h/day, 5 days a week for 8 weeks.
Exercise training increased the percent of venous oxyhemoglobin and sharply decreased …
Considering that regular exercise exerts multiple beneficial health effects including anti-
inflammatory actions, we investigated whether a treadmill training program could minimize
the inflammatory state in transgenic sickle cell (SS) mice. To test this hypothesis, SS mice
were subjected to a treadmill training protocol of 1 h/day, 5 days a week for 8 weeks.
Exercise training increased the percent of venous oxyhemoglobin and sharply decreased …