[HTML][HTML] Abnormal modulation of cell protective systems in response to ischemic/reperfusion injury is important in the development of mouse sickle cell hepatopathy

A Siciliano, G Malpeli, OS Platt, C Lebouef… - …, 2011 - ncbi.nlm.nih.gov
A Siciliano, G Malpeli, OS Platt, C Lebouef, A Janin, A Scarpa, O Olivieri, E Amato…
Haematologica, 2011ncbi.nlm.nih.gov
Background Sickle cell disease, a genetic red cell disorder inherited in an autosomal
recessive manner, occurs throughout the world. Hepatic dysfunction and liver damage may
be present in sickle cell disease, but the pathogenesis of these conditions is only partially
understood.
Abstract
Background
Sickle cell disease, a genetic red cell disorder inherited in an autosomal recessive manner, occurs throughout the world. Hepatic dysfunction and liver damage may be present in sickle cell disease, but the pathogenesis of these conditions is only partially understood.
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