Delayed onset and protracted progression of anaphylaxis after omalizumab administration in patients with asthma

SL Limb, PR Starke, CE Lee, BA Chowdhury - Journal of allergy and clinical …, 2007 - Elsevier
BACKGROUND: Risk of anaphylaxis is included in the prescribing information for
omalizumab, but the nature of these reactions merits further elaboration. OBJECTIVE: To
describe cases of anaphylaxis associated with omalizumab administration in patients with
asthma. METHODS: We reviewed spontaneous postmarketing adverse event reports
submitted to the US Food and Drug Administration's Adverse Event Reporting System
database and to the manufacturers of omalizumab and cases published in the literature …