Chondroitin sulphate proteoglycans in the CNS injury response

DA Morgenstern, RA Asher, JW Fawcett - Progress in brain research, 2002 - Elsevier
Publisher Summary This chapter focuses on the changes in the expression of the axon
growth-inhibitory chondroitin sulphate proteoglycans (CSPGs). CSPGs represent a varied
class of complex extracellular matrix macromolecules. They share a general molecular
structure comprising a central core protein with a number of covalently attached
carbohydrate chains known as “glycosaminoglycans”(GAG). The experimental data
indicates that the expression of a number of different CSPGs is increased following central …