[HTML][HTML] Examining the current standards for genetic discovery and replication in the era of mega-biobanks
JE Huffman - Nature communications, 2018 - nature.com
Nature communications, 2018•nature.com
With the recent deluge of mega-biobank data, it is time to revisit what constitutes “replication”
for genome-wide association studies. Many replication samples are unavailable or
underpowered, therefore alternatives beyond strict statistical replication are needed until the
required resources become available.
for genome-wide association studies. Many replication samples are unavailable or
underpowered, therefore alternatives beyond strict statistical replication are needed until the
required resources become available.
Abstract
With the recent deluge of mega-biobank data, it is time to revisit what constitutes “replication” for genome-wide association studies. Many replication samples are unavailable or underpowered, therefore alternatives beyond strict statistical replication are needed until the required resources become available.
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